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HIV integrase inhibitors from pyridoxine
专利权人:
Brent Stranix
发明人:
Brent Stranix,Francis Beaulieu,Jean-Emmanuel Bouchard,Guy Milot,Wang Zhigang,Réjean Ruel
申请号:
US12995890
公开号:
US08742123B2
申请日:
2009.06.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to pyridoxine (vitamin B6) derived compounds of formula (I), pharmaceutically acceptable salts, or solvates thereof, wherein R1, R2, R4, A, L B1 and B2 are as defined in the specification, and pharmaceutical compositions comprising the compounds. Compounds of formula (I) inhibit Human Immunodeficiency Virus (HIV)-integrase enzyme and are useful for preventing and treating HIV infection and AIDS.
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