A system for ablation planning and treatment includes a delineation module (124) configured to distinguish tissue types in an image, the tissue types including at least a core tissue and a margin zone encapsulating the core tissue. A treatment planning module (140) is configured to apply weightings in a cost function to prioritize ablation coverage of the tissue types including the core tissue and the margin zone to determine ablation characteristics that achieve an ablation composite in accordance with user preferences. A graphical user interface (122) is rendered on a display to indicate the core tissue, the margin zone, the ablation composite and permit module user selection of one or more treatment methods.