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SUSPENSION CONTENANT DES NANOPARTICULES D'ACIDE SILICIQUE COLLOÏDALES STABILISÉES À L'HYDRONIUM, FORMULATION OBTENUE À PARTIR DE LADITE SUSPENSION DILUÉE, POUDRE OBTENUE À PARTIR DE LADITE SUSPENSION DÉSHYDRATÉE, COMPOSITIONS OBTENUES À PARTIR DE LADITE POUDRE, PRÉPARATION ET UTILISATION
专利权人:
Jisbrey, S.A;Aquarius Investholding S.à.r.l.
发明人:
申请号:
EP09753742.7
公开号:
EP2271588B2
申请日:
2009.04.16
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to hydronium stabilized silicic acid nanoparticles, to the formulation obtained from the said diluted suspension, to the powder obtained from the said dehydrated suspension and to the preparation or dosage form obtained from the said suspension, formulation or powder, to their preparation and their use in all kinds of applications in the domains of food, medicine, pharmaceutics, cosmetics. The present invention provides a stable suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, a molar silicon concentration between 0.035 and 0.65, a free water concentration of at least 30% (w/v) and a ratio between hydronium ion and Si molar concentrations higher than 2 and preferably inferior to 4. The present invention further provides a method for preparing a stable suspension of colloidal silicic acid nanoparticles, which comprises the steps of providing an aqueous inorganic or organic silicon solution and quick mixing said aqueous inorganic or organic silicon solution with water containing a strong acidic compound at a temperature inferior at 30° C., preferably comprised between 1 and 25° C., to form a suspension of colloidal silicic acid nanoparticles having a pH lower than 0.9, stabilized by hydronium ions, the ratio between hydronium ions and Si molar concentrations being higher than 2 and preferably inferior to 4, for a molar silicon concentration between 0.035 and 0.65 and a free water concentration of at least 30% (w/v).
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