A first aspect of the invention is related to a method for treating a subject's tooth that needs regeneration of dental enamel tissue and/or ameloblast cells. This method includes exposing at least a portion of crown, root canal or periapical tissue of the tooth and administering an enamel material in an amount sufficient to promote the regeneration of dental enamel tissue and/or ameloblast cells such that at least a portion of the exposed crown, root canal or periapical tissue is in contact with the enamel material. The invention is also related to a kits, compositions, and devices which can be used for the purposes of the present invention.
