薬剤の副作用を緩和する活性を有する物質の評価方法及びスクリーニング方法、並びに、これらの方法により同定された物質を有効成分とする副作用緩和剤
- 专利权人:
- 株式会社ゲノム創薬研究所
- 发明人:
- 浜本 洋,関水 和久
- 申请号：
- JP2006209972
- 公开号：
- JP5219013B2
- 申请日:
- 2006.08.01
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a method for efficiently and easily evaluating and screening the substance for alleviating the side effect of a medicine on an organism having an acquired immunological mechanism, and a side effect alleviating agent for alleviating the side effect of the medicine on the organism having the acquired immunological mechanism by utilizing the substance evaluated and screened by that method.
SOLUTION: The evaluation method includes the process (a) of admistering the medicine and a substance to be examined to the organism having only a natural immunological mechanism, the process (b) of detecting the side effect of the medicine on the organism having the natural immunological mechanism and the process (c) of evaluating whether the substance to be examined alleviates the side effect and the screening method further includes the process (d) of selecting the substance evaluated to alleviate the side effect. The side effect alleviating agent contains edible oil as an effective component to alleviate the side effect of the medicine.
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- 来源网站：
- 中国工程科技知识中心
