PROBLEM TO BE SOLVED: To provide a novel liver fat accumulation inhibitor.SOLUTION: The present invention provides liver fat production enzyme inhibitors comprising protein derived from Vigna radiata seeds as an active ingredient, particularly hepatic stearoyl-CoA desaturation enzyme 1 (Scd-1) inhibitors. The present invention also provides liver fat accumulation inhibitors comprising the inhibitors as an active ingredient.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2017,JPO&INPIT【課題】 本発明は、新規な肝臓脂肪蓄積抑制剤を提供することを目的とする。【解決手段】緑豆由来のタンパク質を有効成分とする、肝臓脂肪産生酵素阻害剤、特に肝臓ステアロイル‐CoA不飽和化酵素1(Scd-1)の阻害剤による。また当該阻害剤を有効成分とする、肝臓脂肪蓄積抑制剤による。【選択図】図1