Marina V. Brockway;Carlos Haro;Kent Lee;Krzysztof Z. Siejko;Abhilash Patangay;Richard O. Kuenzler;Yi Zhang;Gerrard M. Carlson;Yousufali Dalal;John D. Hatlestad
发明人:
Yi Zhang,John D. Hatlestad,Gerrard M. Carlson,Yousufali Dalal,Marina V. Brockway,Kent Lee,Richard O. Kuenzler,Carlos Haro,Krzysztof Z. Siejko,Abhilash Patangay
申请号：
US13845398
公开号：
US20130226078A1
申请日:
2013.03.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm whose presence, absence, or baseline change is associated with impending disease, and comparing such rhythm to baseline circadian rhythm prediction criteria. Other chronobiological rhythms beside circadian may also be used. The baseline prediction criteria may be derived using one or more past physiological process observation of the subject or population of subjects in a non-disease health state. The prediction processing may be performed by the at least one implantable device or by an external device in communication with the implantable device. Systems and methods for invoking a therapy in response to the health state, such as to prevent or minimize the consequences of predicted impending heart failure, are also discussed.
