The present invention relates to melamine resins having incorporated therein one or more antimicrobial agents, where one of the antimicrobial agents is an isothiazolone based compound. The melamine resin is compounded with the antimicrobial as a finely divided powder diluted in a liquid forming a dispersion. The compounded melamine resin is useful for making melamine based decorative laminates used in flooring, countertops, dinnerware and other applications wherein a tough, mar resistant surface having bactericidal properties is required.