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MMP13 BINDING IMMUNOGLOBULINS
专利权人:
ABLYNX NV;Merck Patent GmbH
发明人:
Francis DESCAMPS,Gerald BESTE,Guy HERMANS,Hans GUEHRING,Lars TOLEIKIS,Christoph LADEL
申请号:
US16617869
公开号:
US20200190216A1
申请日:
2018.06.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to immunoglobulins that specifically bind MMP13 and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the immunoglobulins of the present invention inhibit an activity of MMP13 and preferably are also stable.
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