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NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF
专利权人:
Hideaki TADA;Shiro SHIBAYAMA;Tatsuya TANIHIRO;Hiromu HABASHITA;Masaya KOKUBO
发明人:
Hiromu HABASHITA,Masaya KOKUBO,Shiro SHIBAYAMA,Hideaki TADA,Tatsuya TANIHIRO
申请号:
US13402033
公开号:
US20120156219A1
申请日:
2012.02.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The compound represented by formulae (I) and (II), the salt thereof, the N-oxide thereof or the solvate thereof, or the prodrug thereof and the pharmaceutical composition comprising thereof have a CXCR4-regulating effect, and they are effective in treatment and prevention of various inflammatory disease, various allergic disease, acquired immunodeficiency syndrome infection with human immunodeficiency virus, or agents for regeneration therapy.(wherein ring A represents a nitrogen-containing heterocyclic group which may have a substituent(s); ring B represents a homocyclic group which may have a substituent(s) or a heterocyclic group which may have a substituent(s); and Y represents a hydrocarbon group which may have a substituent(s), a heterocyclic group which may have a substituent(s), an amino group which may be protected, a hydroxyl group which may be protected or a mercapto group which may be protected; T represents ring A or an amino group which may be protected.)
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