DÉRIVÉS D'INDANONE, SELS PHARMACEUTIQUEMENT ACCEPTABLES OU ISOMÈRES OPTIQUES CORRESPONDANTS, PROCÉDÉ DE PRÉPARATION DE CEUX-CI ET COMPOSITIONS PHARMACEUTIQUES LES CONTENANT EN TANT QU'INGRÉDIENT ACTIF POUR LA PRÉVENTION OU LE TRAITEMENT DE MALADIES VIRALES
Korea Research Institute of Chemical Technology;Katholieke Universiteit Leuven
发明人:
申请号：
EP19169080.9
公开号：
EP3597184A2
申请日:
2012.06.18
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention relates to a novel indanone derivative, pharmaceutically acceptable salts or optical isomers thereof, a preparation method for same, and a pharmaceutical composition containing same as an active ingredient for preventing or treating viral diseases. The indanone derivatives according to the present invention not only have low cyto-toxicity, but can also demonstrate utility as pharmaceutical compositions for preventing or treating viral diseases such as:； polio, viral paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand-foot-mouth disease, blistering diseases, hepatitis A, myositis, myocarditis, pancreatitis, viral diabetes, epidemic myalgia, encephalitis, flu, herpes angina, foot- and-mouth disease, asthma, chronic obstructive pulmonary disease, pneumonia, sinusitis, otitis media, and the like, since excellent antiviral activity against picornaviruses such as Coxsackie virus, enterovirus, echovirus, polio virus, rhinovirus, and the like, have been demonstrated.
