UNIVERSITÀ DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO"
发明人:
Armando A. GENAZZANI,Gian Cesare TRON,Ubaldina GALLI,Cristina TRAVELLI,Salvatore CUZZOCREA,Giorgio GROSA,Giovanni SORBA,Pier Luigi CANONICO
申请号:
US14888597
公开号:
US20160075682A1
申请日:
2014.04.29
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds of formula (I): able to inhibit nicotinamide phosphoribosyltransferase. The disclosure also relates to the use of compounds of formula (I) for treatment of pathological conditions in which NAMPT inhibition might be beneficial, such as acute and chronic inflammation, cancer and metabolic disorders.