Rekombinant variant av Lol p 5 protein allergen med redusert IgE-binding, anvendelse derav samt sammensetning.

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专利权人:

THE UNIVERSITY OF MELBOURNE

发明人:

SINGH MOHAN BIR,DEWEERD NICOLE,BHALLA PREM L,SWOBODA INES

申请号：

NO20041146

公开号：

NO336740B1

申请日:

2004.03.19

申请国别(地区):

NO

年份:

2015

代理人:

摘要：

The present invention relates generally to reagents useful in the immunotherapeutic or immunoprophylactic treatment of allergic diseases. More particularly, the present invention provides modified allergens exhibiting reduced IgE interactivity including reduced IgE production-stimulatory activity, while retaining T-cell antigenicity, which are useful in the immunomodulation of type I allergic disease conditions. The present invention further contemplates a method of immunomodulation of allergic diseases such as type I allergic disease conditions by the administration of modified allergens exhibiting reduced IgE interactivity while retaining T-cell antigenicity.

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中国工程科技知识中心

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