Virginia Commonwealth University;Enzo Therapeutics, Inc.
发明人:
Sarah Spiegel,Robert Elliot Zipkin,Jeffrey Kroll Adams
申请号:
US15181826
公开号:
US09974758B2
申请日:
2016.06.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are inhibitors of sphingosine kinase Type I that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (GBM).