Fibrosis of the eye problems (eg, fibrosis that occurs during the treatment of glaucoma by trabeculectomy) may provide methods and compositions for the treatment of. Enzyme lysyl oxidase type of one or more (eg, LOX, LOXL2) includes modulators of activity, methods, and methods for preparing the regulators A1 A composition, the administration of the modulator I and a method of administering the regulatory factor to a subject in need. [Selection] Figure Figure 1【課題】眼の繊維症(例えば、線維柱帯切除術による緑内障の処置の間に生じる繊維症)の処置のための方法及び組成物を提供すること。【解決手段】組成物は、1つ以上のリシルオキシダーゼ型の酵素(例えば、LOX、LOXL2)の活性の調節因子を含み、方法は、該調節因子を調製する方法と、該調節因子の投与を必要とする被験体に当該調節因子を投与する方法とを含む。【選択図】図1
