The invention comprises a method and apparatus for proton treatment of a tumor, comprising the steps of a central control system: (1) receiving an initial cancer treatment irradiation plan; (2) directing a treatment of the tumor using the positively charged particles; (3) during a treatment session and after the step of directing the treatment of the tumor, receiving imaging input from an imaging system; (4) generating an updated cancer treatment irradiation plan using the imaging input; (5) continuing the treatment session using the updated cancer treatment irradiation plan; and (6) optionally, while the patient remains in the treatment room and under approval of a medical professional not in line of sight of the patient, repeating at least three times the steps of: receiving imaging input from the imaging system; generating an updated cancer treatment irradiation plan; and continuing the treatment session using the updated cancer treatment irradiation plan.