The polypeptide of the invention discloses a kind of specific binding Ror2 albumen with heavy chain variable region and/or light chain variable region, and comprising heavy chain variable region and/or light chain variable region with the protein bound antibody of Ror2 and antibody fragment. Additionally provide pharmaceutical composition and kit comprising the polypeptide or comprising the antibody containing the polypeptide and antibody fragment.本發明公開了一種具有重鏈可變區和／或輕鏈可變區的特異性結合Ror2蛋白的多肽，以及包含重鏈可變區和／或輕鏈可變區的與Ror2蛋白結合的抗體和抗體片段。還提供了包含所述多肽或者包含含有所述多肽的抗體和抗體片段的藥物組合物和試劑盒。
