BLANEY, JEFFREY,GIBBONS, PAUL A.,HANAN, EMILY,LYSSIKATOS, JOSEPH P.,MAGNUSON, STEVEN R.,PASTOR, RICHARD,RAWSON, THOMAS E.,ZHOU, AIHE,ZHU, BING-YAN
申请号:
CA2740792
公开号:
CA2740792C
申请日:
2009.11.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The invention provides JAK kinaseinhibitors of Formula Ia, enantiomers,diasteriomers or pharmaceutically acceptablesalts thereof, wherein R1, R2, R7 and Z aredefined herein, a pharmaceutical composition thatincludes a compound of Formula la and a pharmaceuticallyacceptable carrier, adjuvant or vehicle,and methods of treating or lessening theseverity of a disease or condition responsive tothe inhibition of a JAK kinase activity in apatient. la