Tushar A. Parlikar,Gireeja V. Ranade,Thomas Heldt,George C. Verghese
申请号：
US12121042
公开号：
US08282564B2
申请日:
2008.05.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The methods and systems for estimating cardiac output and total peripheral resistance include observing arterial blood pressure waveforms to determine intra-beat and inter-beat variability in arterial blood pressure and estimating from the variability a time constant for a lumped parameter beat-to-beat averaged Windkessel model of the arterial tree. Uncalibrated cardiac output and uncalibrated total peripheral resistance may then be calculated from the time constant. Calibrated cardiac output and calibrated total peripheral resistance may be computed using calibration data, assuming an arterial compliance that is either constant or dependent on mean arterial blood pressure. The parameters of the arterial compliance may be estimated in a least-squares manner.
