LELLOUCHE, JEAN PAUL,MICHAELI, SHULAMIT,ISRAEL, LIRON LIMOR,LELLOUCHE, EMMANUEL,KAPILOV-BUCHMAN, YEKATERINA
申请号:
EP14769361
公开号:
EP2976293A4
申请日:
2014.01.19
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
A nanoparticle, which has a metal oxide core and a cerium shell is provided. The weight ratio of the cerium within the shell to the metal oxide in the core is at least 1%. Additionally a method for delivering a ligand into a cell with the nanoparticle is provided. Processes for making the nanoparticle which include: sonicating an aqueous composition containing Ceric Ammonium Nitrate and a prefabricated nanoparticle suspension; and (b) adding a polycationic polymer to the mixture (for NP surface functionalization), are also described