Ellen Gomme,Gerard Griffioen,Hein Roger Duhamel,Ingrid Van Der Auwera,Kristel Marie Edith Coupet,Marleen Lox,Nele Van Damme,Stefaan Wera,Tine Decruy,Tom Van Dooren
申请号：
BRPI0707700
公开号：
BRPI0707700B1
申请日:
2007.02.07
申请国别(地区):
BR
年份:
2020
代理人:
摘要：
thiadiazole derivatives for the treatment of neurodegenerative diseases. the present invention relates to 1,2,4-thiadiazole derivatives specifically substituted for use in the treatment of a-synucleopathy, such as parkinson's disease, diffuse lewy corpuscles disease, traumatic brain injury, amyotrophic lateral sclerosis, niemann-pick syndrome, hallervorden-spatz syndrome, down syndrome, neuraxonal dystrophy, multiple system atrophy and alzheimer's disease.derivados de tiadiazol para tratamento de doenças neurodegenerativas. a presente invenção refere-se a derivados de 1,2,4-tiadiazol especificamente substituído para uso no tratamento de uma a-sinucleopatia, tal como mal de parkinson, doença difusa dos corpúsculos de lewy, lesão cerebral traumática, esclerose amiotrófica lateral, doença de niemann-pick, síndrome hallervorden-spatz, síndrome de down, distrofia neuroaxonal, atrofia de sistemas múltiplos e mal de alzheimer.
