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FORMAS DE SAL E CRISTAL DE INIBIDOR DE PLK-4
专利权人:
UNIVERSITY HEALTH NETWORK
发明人:
PETER BRENT SAMPSON,MIKLOS FEHER,HEINZ W. PAULS
申请号:
PT14854037
公开号:
PT3057965T
申请日:
2014.10.17
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
A fumarate salt and a maleate salt of compound (I) represented by the following structural formula, as well as their corresponding pharmaceutical compositions, are disclosed. Particular single crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are also disclosed. The present invention also provides methods of treating a subject with a cancer. Compound (I)
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