A method of manufacturing a manifold pad (111) that is, at least in part, radio opaque includes providing a manifold member (112) having a plurality of flow channels; providing a radioopacifier; and heating the manifold member (112) and the radioopacifier in a heating vessel at an elevated temperature to form the manifold pad (111). The manifold pad (111) may distribute reduced pressure at a tissue site and allow for detection using radiography. Systems (100), manifold pads (111), and other methods are also presented.