Described herein are methods of treating a disorder,e.g., tremor,e.g.,essential tremor； depression,e.g.,postpostum depression； and anxiety disorder, the method comprising administering to a human subject suffering from a disorder,e.g., tremor,e.g.,essential tremor； depression,e.g.,postpostum depression, an anxiety disorder with a neuroactive steroid or a composition comprising a neuroactive steroid (e.g.,pregnanolone, allopregnanolone, alphadalone, ganaxolone, or alphaxolone).本文闡述治療病症(例如震顫，例如自發性震顫；抑鬱症，例如生產後抑鬱症；及焦慮症)之方法，該方法包含向患有病症(例如震顫，例如自發性震顫；抑鬱症，例如生產後抑鬱症；焦慮症)之人類個體投與神經活性類固醇(例如孕烷醇酮(pregnanolone)、別孕烷醇酮(allopregnanolone)、阿法達龍(alphadalone)、加奈索酮(ganaxolone)或阿法克龍(alphaxolone))或包含神經活性類固醇之組合物。
