#$%^&*AU2015207901A120150820.pdf#####ABSTRACT Methods of using SNS-595 for treatment of a subject having cancer with BRCA2 mutation are described. In certain embodiments, the methods comprise administering a therapeutically effective amount of SNS-595 to a subject in need thereof.FIGURE 1 120 -Eg- VC 8 100 ~-3- VC8-B2 800 40 200 0 0.1 0.2 0.3 0.4 0.5 06 Doxorubicin (pM) 1/10