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5-Phenyl-pentanoic acid derivatives as inhibitors of matrix metalloproteinase for the treatment of asthma and other diseases
- 专利权人:
- RANBAXY LABORATORIES LIMITED;RANBAXY LABORATORIES LIMITED
- 发明人:
- PALLE, VENKATA,SATTIGERI, VISWAJANANI,KHERA, MANOJ,VOLETI, SREEDHARA,RAY, ABHIJIT,DASTIDAR, SUNANDA
- 申请号：
- ES06727254
- 公开号：
- ES2381681T3
- 申请日:
- 2006.02.21
- 申请国别(地区):
- ES
- 年份:
- 2012
- 代理人:
- 摘要：
- Compound which is: 5-biphenyl-4-yl-3-hydroxy-2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (compound No. 1) , 2- (2 - {[(benzyloxy) carbonyl] amino} ethyl) -5-biphenyl-4-yl-3-hydroxypentanoic acid (compound No. 11), 5-biphenyl-4-yl-3-hydroxy-2 acid - {2- [(phenylacetyl) amino] ethyl} pentanoic acid (compound No. 45), 5-biphenyl-4-yl-3-hydroxy-2- [2- (1-oxophthalazin-2 (1H) -yl) ethyl ] pentanoic acid (compound No. 47), 5-biphenyl-4-yl-3-hydroxy-2- [2- (2'-oxospiro [cyclopropan-1, 3'-indole] -1 '(2H) -yl) ethyl] pentanoic acid (compound No. 49), 3-hydroxy-2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H) ethyl] -5- [4'- (trifluoromethyl) biphenyl- 4-yl] pentanoic acid (compound No. 59), 5- (3 ', 4'-difluorobiphenyl-4-yl) -3-hydroxy-2- [2- (4-oxo-1, 2, 3-benzotriazin-] 3 (4H) -yl) ethyl] pentanoic acid (compound No. 60), 3-hydroxy-5- (4'-methoxybiphenyl-4-yl) -2- [2- (4-oxo-1, 2, 3- benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (compound No. 64), 5- (4'-chlorobiphenyl-4-yl) -3-hydroxy-2- [2- ( 4-oxo-1,2,3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (compound No. 65), 3-hydroxy-5- [4- (6-methoxypyridin-3-yl) phenyl] - 2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (compound No. 67), 3-hydroxy-5- (4'-methylbiphenyl-4-yl ) -2- [2- (5-methyl-1, 3-dioxo-1, 3-dihydro-2H-isoindol-2-yl) ethyl] pentanoic acid (compound No. 68), 5- (4'-chlorobiphenyl- 4-yl) -3-hydroxy-2- [2- (5-methyl-1, 3-dioxo-1, 3-dihydro-2H-isoindol-2-yl) ethyl] pentanoic acid (compound No. 69), acid 3 -hydroxy-2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H) -yl) ethyl] -5- [4'- (trifluoromethoxy) biphenyl-4-yl] pentanoic acid (compound No. 70), 5- (4'-Fluorobiphenyl-4-yl) -3-hydroxy-2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid ( compound No. 71), 3-hydroxy-5- (4'-methylbiphenyl-4-yl) -2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H) -yl) ethyl] pentanoic acid (compound No. 72), 5- (4'-cyanobiphenyl-4-yl) -3-hydroxy-2- [2- (4-oxo-1, 2, 3-benzotriazin-3 (4H
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
