A biopsy device (10) may include a needle (102), a cutter (130), and a handpiece. A vacuum pump (80) may be provided in the handpiece for providing a vacuum to the needle and/or to the cutter. A motor (42) may be provided in the handpiece to drive the vacuum pump and/or the cutter. A biopsy device may also include a valving mechanism (20) within the handpiece for selectively communicating a vacuum and/or atmospheric air to the needle. A clutching mechanism may selectively provide communication between a motor and the cutter. Portions of a valving mechanism and a clutching mechanism may be integrally formed. A clutching and valving mechanism may be driven by a first motor and a cutter and vacuum pump by a second motor. A biopsy device may include batteries for powering motors. A biopsy device may thus provide vacuum and power from within a handpiece, such that the biopsy device is tetherless.
