Combination of a Derivative of 4 - oxo - 1.6 - dihydro - pyridazine hydrochloride has anticancer activity with an inhibitor of mitogen activated protein kinase (MEK)
MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
发明人:
MANJA DR. FRIESE-HAMIM,FRIEDHELM DR. BLADT
申请号：
ARP130103703
公开号：
AR092991A1
申请日:
2013.10.11
申请国别(地区):
AR
年份:
2015
代理人:
摘要：
A Pharmaceutical composition comprising 3 - (1 - {3 - [5 - (1 - methyl - ilmetoxi piperidin-4-yl) 2] - pyrimidine - il - 6 - benzyl) - oxo - 1.6 - dihydro - 4 - il) pyridazin-3 - Benzonitrile or one of its Salts or solvates and pharmaceutically acceptable and N - ((S) - 2,3-dihydroxy propyl) - 3 - (2-fluoro-4 - Iodine - phenylamino) - or isonicotinamide One of its pharmaceutically acceptable Salts and / or solvates.Una composición farmacéutica que comprende 3-(1-{3-[5-(1-metil-piperidin-4-ilmetoxi)-pirimidin-2-il]-bencil)-6-oxo-1,6-dihidro-piridazin-3-il)-benzonitrilo o una de sus sales y/o solvatos farmacéuticamente aceptables y N-((S)-2,3-dihidroxi-propil)-3-(2-fluoro-4-yodo-fenilamino)-isonicotinamida o una de sus sales y/o solvatos farmacéuticamente aceptables.
