Stephan WAWRA,Pieter VAN WEST,Christopher John SECOMBES
申请号:
US14894659
公开号:
US20160120975A1
申请日:
2014.05.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A composition comprising a translocation sequence derived from a fish pathogen and a heterologous payload coupled to the translocation sequence is provided. The composition is able to translocate across the plasma membrane of a eukaryotic cell, for example a fish cell, and thus stimulate an immune response. Accordingly, nucleic acids, vectors, host cells, compositions and vaccines based thereon are also provided.