It is the important diagnostic technic which magnetic resonance image conversion (on usually depends 1 H as a magnetic nucleus and) is used for the diagnosis of the disease generally at the hospital. MRI makes the non invasion Characteristic image conversion of the soft system which shows the three-dimensional analysis which is superior possible. The magnetic resonance image conversion which uses 19 F in place of 1 H brings new diagnostic possibility. 19 F nuclei high gyro magnetic ratio (40MHz/T) and have 100% natural isotopic ratio. For example with the body of the human as for 19 F content structures it exists monopolistically with configuration of the solid-state salt in the gearwheel and the bone. J2 relaxation time of the endogenous 19 F atom quite is brief as a result, almost cannot detect the MR signal. The very low MRI signal background mortgage is done due to the fact that the endogenous 19 F structure which has relatively high transverse axis relaxation time does not exist. Therefore for example as for extrinsic 19 F MRI contraa medium other technology (PET (positive electron emission tomography))With similar feature hot spot image conversion is made possible. As a useful expansion of the diagnostic use in addition as for MRI for example the living body active material (the curative medicine or the diagnostic glaze) it is recommended because of monitoring of delivery. Namely, MRI can also use using for planning the treatment planning not only as little as possible in order to manage the medicine delivery of deletion the image as a guidepost.磁気共鳴画像化(通常は磁性核として1Hによる)は疾患の診断に病院で一般的に用いられる重要な診断技術である。MRIは優れた立体的解析を示す軟組織の非侵襲性画像化を可能にする。1Hの代わりに19Fを用いる磁気共鳴画像化は新規な診断可能性をもたらす。19F核は高いジャイロマグネティック比(40MHz/T)及び100%の天然同位体存在比を有する。人間の体では19F含有構造物は例えば歯及び骨において固体塩の形態で独占的に存在する。結果として内因性19F原子のJ2緩和時間は極めて短く、MRシグナルはほとんど検出できない。相対的に高い交軸緩和時間をもつ内因性19F系構造物が存在しないことによって非常に低いMRIシグナルバックグラウンドが担保される。したがって外因性19F系MRI造影剤は他の技術(例えばPET(陽電子放射断層撮影法))と類似の態様で“ホットスポット”画像化を可能にする。その診断的使用の有用な拡張としてMRIはまた生体活性物質(例えば
