Disclosed is an electrical signal applicable multi-needle syringe. The present invention comprises: a hollow cylinder a needle hub closely coupled to the rear end of the cylinder a plurality of needles placed at regular intervals inside the cylinder in such a way that the front ends are further protruded compared with the front end of the cylinder and the drug which is injected through the needle hub is sucked through the rear ends a first electrode stored inside the cylinder, and commonly connected to a part of the plurality of needles and a second electrode stored inside the cylinder, and commonly connected with the rest of the plurality of needles. Therefore, it is possible to inject a drug and to simultaneously apply a high frequency directly into the skin through a multi-needle injected into the skin by applying a high frequency between the first electrode and the second electrode, thereby promoting the activation of the injected drug.
