HUMMERSONE, MARC GEOFFREY,GOMEZ, SYLVIE,MENEAR, KEITH ALLAN,SMITH, GRAEME, CAMERON, MURRAY,MALAGU, KARINE,DUGGAN, HEATHER MARY ELLEN,COCKCROFT, XIAO-LING FAN,HERMANN, GESINE JOHANNA
申请号：
HRP20120963
公开号：
HRP20120963T1
申请日:
2012.11.27
申请国别(地区):
HR
年份:
2012
代理人:
摘要：
There is provided a compound of formula I: wherein: one or two of X<；SUP>；5<；/SUP>；, X<；SUP>；6 <；/SUP>；and X<；SUP>；8 <；/SUP>；is N, and the others are CH； R<；SUP>；7 <；/SUP>；is selected from halo, OR<；SUP>；O1<；/SUP>；, SR<；SUP>；S1<；/SUP>；, NR<；SUP>；N1<；/SUP>；R<；SUP>；N2<；/SUP>；, NR<；SUP>；N7a<；/SUP>；C(-O)R<；SUP>；C1<；/SUP>；, NR<；SUP>；N7b<；/SUP>；SO<；SUB>；2<；/SUB>；R<；SUP>；S2a<；/SUP>；, an optionally substituted C<；SUB>；5-20 <；/SUB>；heteroaryl group, or an optionally substituted C<；SUB>；5-20 <；/SUB>；aryl group, where R<；SUP>；O1 <；/SUP>；and R<；SUP>；S1 <；/SUP>；are selected from H, an optionally substituted C<；SUB>；5-20 <；/SUB>；aryl group, an optionally substituted C<；SUB>；5-20 <；/SUB>；heteroaryl group, or an optionally substituted C<；SUB>；1-7 <；/SUB>；alkyl group； R<；SUP>；N1 <；/SUP>；and R<；SUP>；N2 <；/SUP>；are independently selected from H, an optionally substituted C<；SUB>；1-7 <；/SUB>；alkyl group, an optionally substituted C<；SUB>；5-20 <；/SUB>；heteroaryl group, an optionally substituted C<；SUB>；5-20 <；/SUB>；aryl group or R<；SUP>；N1 <；/SUP>；and R<；SUP>；N2 <；/SUP>；together with the nitrogen to which they are bound form a heterocyclic ring containing between 3 and 8 ring atoms； R<；SUP>；C1 <；/SUP>；is selected from H, an optionally substituted C<；SUB>；5-20 <；/SUB>；aryl group, an optionally substituted C<；SUB>；5-20 <；/SUB>；heteroaryl group, an optionally substituted C<；SUB>；1-7 <；/SUB>；alkyl group or NR<；SUP>；N8<；/SUP>；R<；SUP>；N9<；/SUP>；, where R<；SUP>；N8 <；/SUP>；and R<；SUP>；N9 <；/SUP>；are independently selected from H, an optionally substituted C<；SUB>；1-7 <；/SUB>；alkyl group, an optionally substituted C<；SUB>；5-20 <；/SUB>；heteroaryl group, an optionally substituted C<；SUB>；5-20 <；/SUB&g
