surface modified particle, pharmaceutical composition, method for enhancing cellular absorption of an active agent, use of a plurality of surface modified particles, and, plurality of surface modified particles
BARRETT RABINOW,JANE WERLING,MAHESH V. CHAUBAL,SARAH LEE,SHAWN F. BAIRSTOW
申请号:
BRPI1010903
公开号:
BRPI1010903A2
申请日:
2010.05.13
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present disclosure is directed to surface-modified particles and to methods of making and using the same. The surface-modified particles comprise a particle core and a coating associated with the particle core, wherein the particle core comprises an active agent, the coating comprises a surfactant having formula I, and the surface-modified particle has an average size from about 1 nm to about 2,000 nm: