Jinsheng Chen;Sanath K. Meegalla;Shelley K. Ballentine;Mark Wall;Kenneth Wilson;Renee Louise DesJariais;Carl R. Illig
发明人:
Carl R. Illig,Shelley K. Ballentine,Jinsheng Chen,Renee Louise DesJariais,Sanath K. Meegalla,Mark Wall,Kenneth Wilson
申请号：
US11736635
公开号：
US08674100B2
申请日:
2007.04.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention is directed to compounds of Formula I:wherein Z, X, J, R2 and W are as set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. The compounds of formula I are useful for treating a variety of disorders including autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and psoriasis.
