A loading unit for engagement with a surgical instrument. The loading unit includes a proximal body portion, an end effector, an actuation sled, and pushers. The actuation sled is longitudinally translatable within a cartridge assembly. The pushers are disposed within the cartridge assembly. Each pusher includes a camming surface configured for engagement with the actuation sled. The camming surface of each pusher in a first row is longitudinally aligned with the camming surface of each pusher in a second row. The first row of pushers is laterally offset from the second row of pushers.