[PROBLEMS] To provide a compound useful as an agent for the treatment of circulatory diseases, nervous system diseases, metabolic diseases, reproductive system diseases, and digestive tract diseases. [MEANS FOR SOLVING PROBLEMS] The compound, which is for use as an active ingredient, is represented by the formula (I): [wherein R 1 represents optionally halogenated C 1-6 alkyl, etc.； R 2 represents, e.g., a group represented by the formula (II-1) or (II-4) (wherein W represents C 1-6 alkylene, etc. and R represents C 1-6 alkyl, etc.)； R 3 represents hydrogen, C 1-6 alkyl, etc.； X represents -O-, -NH-, etc.； and Y 1 , Y 2 , Y 3 , and Y 4 each independently represents -CH-, -N-, etc.].
