Methods of producing bone graft materials are provided. Aspects of the methods include comminuting an initial bone source to produce a particulate bone composition, cleaning the particulate bone composition and then combining the cleaned particulate bone composition with an organic acid solution in a manner sufficient to produce a bone graft material. Aspects of the invention also include kits that find use in practicing the methods, as well as bone graft materials produced by the methods. The methods and bone graft materials produced thereby find use in a variety of applications, e.g., spinal fusion and bone void filling applications.
