SOMMERFELD, MARK,LANGER, THOMAS,BOSCHEINEN, OLIVER,DREYER, MATTHIAS,DITTRICH, WERNER,HABERMANN, PAUL (DECEASED)
申请号:
CA3006689
公开号:
CA3006689A1
申请日:
2016.12.02
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to polypeptide variants of human fibroblast growth factor 21 (FGF21) and fusion molecules thereof, as well as to nucleic acid molecules encoding the same. It further relates to their use as medicaments, in particularfor the treatment of obesity, overweight, metabolic syndrome, diabetes mellitus, hyperglycemia, dyslipidemia, non-alcoholic steatohepatitis (NASH) and/or atherosclerosis.