PIERRE DESREUMAUX,SALVATORE BELLINVIA,PHILIPPE CHAVATTE,SERGIO BARONI
申请号：
BRPI0820568
公开号：
BRPI0820568A2
申请日:
2008.12.22
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
There is a need for pharmaceutical compounds which have activity at, at least one of a PPAR and a cannabinoid receptor. Thus there are provided such compounds, wherein the compound comprises: a PPAR pharmacophore and a cannabinoid pharmacophore linked together by a moiety comprising a fused bicyclic ring comprising a five membered ring fused with a six membered ring or a six membered ring fused with a six membered ring； wherein the cannabinoid pharmacophore comprises the fused bicyclic ring； and the PPAR pharmacophore comprises a salicylic acid, alkoxybenzylacetic acid or a alkoxyphenylacetic acid functionality； and wherein the PPAR pharmacophore is linked to the bicyclic ring of the cannabinoid pharmacophore through a linker comprising an amine or an amide functional group.
