the invention relates to a new \u0430\u043b\u043a\u0430\u043b\u043e\u0438\u0434\u0443 and new biologically active \u0430\u043b\u043a\u0430\u043b\u043e\u0438\u0434\u043d\u044b\u043c factions obtained from ribes, preferably selected from ribes rubrum and ribes nigrum str \u0441\u043e\u0431\u0430\u043c production of biologically active \u0430\u043b\u043a\u0430\u043b\u043e\u0438\u0434\u043d\u044b\u0445 fractions of ribes and their use for inhibiting ikk - \u03b2,PDE4 and \/ or PDE5 in addition to their enabling operation at \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440\u0438\u0430\u043b\u044c\u043d\u044b\u0439 biogenesis and function and their therapeutic or \u043d\u0435\u0442\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u043c applications as pete \u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 or medicines for the control conditions of the \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440\u0438\u0439 or activity of ikk - \u03b2, PDE4 and \/ or PDE5, such as inflammation, neural degenerative disease \u0434\u0438\u0441\u043b\u0438\u043f\u0438\u0434\u0435\u043c\u0438\u044f, diabetes mellitus type 2violation of the wound healing, sarcopenia, and other related conditions of muscle function or fatigue and \u0443\u0442\u043e\u043c\u043b\u044f\u0435\u043c\u043e\u0441\u0442\u044c\u044e, or where is best \u043c\u0438\u0437\u0430\u0446\u0438\u044f muscle or cognitive function \u044d\u043a\u0441\u0442\u0440\u0430\u043a\u0442\u0430\u043c, \u0441\u043e\u043a\u0430\u043c or \u043a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0442\u0430\u043c of ribes, containing the alkaloid compositions containing such alkaloids, including pharmaceutical compositions, nutritious foodssuch as functional foods and nutraceuticals compositions and cosmetic compositions and products for medical use.Изобретение относится к новому алкалоиду и новым биологически активным алкалоидным фракциям, получаемым из Ribes, предпочтительно выбранным из Ribes rubrum и
