Composition containing glycosylated interferon-beta-1a, pharmaceutical composition, use of composition, in-vitro method of prolonging the activity of interferon-beta-1a and use of polymer moiety
PEPINSKY BLAKE,RUNKEL LAURA,BRICKELMAIER MARGOT,WHITTY ADRIAN,HOCHMAN PAULA
申请号：
SK5062001
公开号：
SK287918B6
申请日:
1999.10.15
申请国别(地区):
SK
年份:
2012
代理人:
摘要：
Described is an interferon-beta-1a composition containing a glycosylated interferon-beta-1a coupled to a non-naturally- occurring polymer at N-terminal end of the interferon-beta-1a, whereby the polymer comprising a polyalkylene glycol moiety, use of the composition in the treatment of cancer tumors, autoimmune conditions, viral diseases or angiogenic diseases, an in-vitro method of prolonging the activity of interferon-beta-1a in an in-vitro system.Described is an interferon-beta-1a composition containing a glycosylated interferon-beta-1a coupled to a non-naturally- occurring polymer at N-terminal end of the interferon-beta-1a, whereby the polymer comprising a polyalkylene glycol moiety, use of the composition in the treatment of cancer tumors, autoimmune conditions, viral diseases or angiogenic diseases, an in-vitro method of prolonging the activity of interferon-beta-1a in an in-vitro system.
