Disclosed is a combination pharmaceutical composition comprising a) a homeopathic activated-potentiated form of an antibody to at least one cytokine and b) a homeopathic activated-potentiated form of an antibody to at least one receptor. Also disclosed is the use of a homeopathic activated-potentiated form of an antibody to at least one cytokine in the preparation of a first medicament for the treatment of infectious disease and use of a homeopathic activated-potentiated form of an antibody to at least one receptor in the preparation of a second medicament for the treatment of infectious disease, for administration substantially at the same time to a patient in need thereof.