Tricycle derivatives with nuclear hormone receptor activity; pharmaceutical components containing these receptors; repair process of intermediate compounds; used in the treatment of AIDS, acute adrenaline failure, Addison's disease, allergic nephritis, NVISM Alzheimer's disease, etc.
CUSACK KEVIN P,GORDON THOMAS D,IHLE DAVID C,HAYES MARTIN E,BREINLINGER ERIC C,ERICSSON ANNA M,LI BIN,WANG LEI,MARTINEZ GLORIA Y,BURCHAT ANDREW,HOBSON ADRIAN D,MULLEN KELLY D,FRIEDMAN MICHAEL,MORYTKO M
申请号:
CL2013002650
公开号:
CL2013002650A1
申请日:
2013.09.13
申请国别(地区):
CL
年份:
2013
代理人:
摘要:
The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.COMPUESTOS DERIVADOS TRICICLICOS CON ACTIVIDAD SOBRE LOS RECEPTORES HORMONALES NUCLEARES; COMPOSICION FARMACEUTICA QUE LOS COMPRENDE; PROCESO DE REPARACION DE COMPUESTOS INTERMEDIARIOS; Y USO EN EL TRATAMIENTO DEL SIDA, INSUFICIENCIA ADRENAL AGUDA, ENFERMEDAD DE ADDISON, RINITIS ALERGICA, ENFERMEDAD DE ALZHEIMER, ENTRE OTROS.