An extended release formulation of a direct thrombin inhibitor

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专利权人:

Diakron Pharmaceuticals Inc.

发明人:

Ramakrishnan, Sankar,Venkatesan, Elumalai,Suryakumar, Jayanthi,Allard, Stephane

申请号：

AU2012336036

公开号：

AU2012336036A1

申请日:

2012.11.06

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

Extended release formulations of 3-fluoro-2-pyridylmethyl-3-(2,2-difluoro-2-(2- pyridyl)ethylamino)-6-chloropyrazin-2-one-l-acetamide (DPOC-4088) that provide for better control of blood plasma levels. The extended release formulations maintain substantially constant plasma levels of the active ingredient for at least about 16 hours and provide for once-daily dosing.

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