LEI SHI;ALEKSA JOVANOVIC;DENNIS CARSON;SMITH & NEPHEW INC.
发明人:
LEI SHI,ALEKSA JOVANOVIC,DENNIS CARSON
申请号：
IL24086415
公开号：
IL240864D0
申请日:
2015.08.26
申请国别(地区):
IL
年份:
2015
代理人:
摘要：
Disclosed is a dissolvable, gel-forming film, and methods for its use, comprising a water-soluble cellulose ether, a hydrophilic rheological modifying agent, and an active proteolytic enzyme or other drug substance. The gel-forming film has a water content of less than 15% w/w and is capable of forming a hydrogel when contacted with water or other aqueous medium. The disclosed films achieve delivery of stable proteolytic enzymes to the desired site of action in a manner that provides uniform delivery of the enzymes.
