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Molecules for bone tissue regeneration
专利权人:
发明人:
Gina Lisignoli,Francesco Grassi,Vincenzo Calderone,Simona Rapposelli
申请号:
US15524257
公开号:
US10016444B2
申请日:
2015.11.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to compounds of general formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ri is selected from an SCN— group or is an RCONH— group in particular, where Ri=RCONH, R is selected from an aromatic benzene ring substituted with an SCN— group in the ortho, meta or para position, according to the following formula: SCN— or R is a C1-C4 alkyl chain, substituted with an SCN— group n can be equal to 0 or else 1. The invention also relates to the use of such compounds for the treatment of osteoporosis and in general of bone pathologies characterized by a progressive loss of bone mass, for example rheumatoid arthritis, hyperparathyroidism or bone tumor metastases.
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