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L-Menthol Dosage Forms Having A Proteinaceous Coating For Enhanced Storage Stability
专利权人:
Zx Pharma; LLC
发明人:
Syed M. Shah,Fred Hassan
申请号:
US14876465
公开号:
US20160022597A1
申请日:
2015.10.06
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A storage stable L-menthol composition including a tablet, caplet, capsule, or sachet dosage form has therein a core containing crystalline L-menthol and at least one pharmaceutical excipient. A proteinaceous coating of a continuous film of proteinaceous material is over the core. The film is effective to substantially prevent the crystalline L-menthol from volatilizing and leaving the core when stored at a temperature of 40 degrees C. and 75% relative humidity from between 1 day to 30 days. The dosage form contains an effective amount of the crystalline L-menthol for treating a gastrointestinal disorder.
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