Mahalaxmi Gita Bangera,Ed Harlow,Roderick A. Hyde,Muriel Y. Ishikawa,Edward K.Y. Jung,Eric C. Leuthardt,Nathan P. Myhrvold,Dennis J. Rivet,Elizabeth A. Sweeney,Clarence T. Tegreene,Lowell L. Wood, JR.
申请号：
US15453103
公开号：
US20170173177A1
申请日:
2017.03.08
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.
