The invention relates to a Chinese medicinal composition for nourishing kidney, tonifying energy, nourishing brain and allaying excitement. The medicinal composition is prepared mainly from the following raw medicinal materials: ginseng, medlar, cherokee rose fruits, sealwort, Chinese dodder seeds, glossy privet fruits, white peony roots, epimedium herb and the like. A preparation method for the composition comprises extraction, concentration, alcohol precipitation, filtration, decolorization, decarbonization, solution preparation and other steps. A quality control method for the composition comprises the steps of determining the total-saponin content of ginseng, the glycoside content of epimedium herb, the amount of persticide residue, and the like. The composition oral liquid has the advantage of definite therapeutic effect of treating cerebral arteriosclerosis, neurasthenia and prostate hyperplasia.