Meinolf Brackhagen,Nicholas S. Grasman,Mark J. Hall,Steven J. Guillaudeu,Robert L. Schmitt,Matthias Knarr
申请号:
US14413080
公开号:
US20150209436A1
申请日:
2013.07.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A liquid composition which comprises an organic liquid diluent and at least one non-ionic cellulose ether having a viscosity of up to 2.33 mPa·s, measured as a 2 wt.-% solution in water at 20° C., is stable over an extended time period. The liquid composition is useful for preparing a solid dispersion comprising at least one active ingredient in at least one cellulose ether by spray-drying. Alternatively a solid dispersion can be produced by blending and extruding at least one active ingredient, at least one cellulose ether having a viscosity of up to 2.33 mPa·s and optionally one or more adjuvants.